Advanced Fibrosis

Pearl Study 

What is the study about?

We are looking for patients with liver cirrhosis caused by one of the underlying conditions of HCV, HBV, alcohol-related, NAFLD and haemochromatosis, who have never been diagnosed with liver cancer.

We are aiming to recruit 20 people to this study. Nation-wide this study aims to recruit 3,000 people.

Who can take part?

Patient who have a diagnosis of advanced liver fibrosis and attend clinic at this hospital.

What is involved?

• We will take a blood and urine sample from you; this will be stored in our research freezer and sent to our central lab partner who will process the samples. They are looking for clues in the blood to help diagnose liver cancer in the future. You will not know the results, because we do not know what these predictors are yet.
• You will complete a brief health questionnaire during recruitment and follow-up.
• We will see you again in 18 months. In the meantime, you do not need to do anything. If you develop liver cancer, we would like you to return for an extra visit to take more blood and urine samples.
• All visits will be completed during your normal liver clinic appointments.
• You will take part in the study for 3 years.
• There are no extra visits to hospital to take part in the study

Tell Me More

More information on the study website

How do I take part?

If you're eligible to take part, your doctor will speak to you at your next routine appointment.